Looking at Guild Wars 2 as an action game
I’ve been doing this since launch and making it more action combat-ish makes the combat a whole ton more entertaining. Although, the auto-targeting is a pain the rear and doesn’t allow for any creativity or versatility in combat (Ex. a lunge with an arcing slash; using the lunge to move off to the side of your opponent just enough as a psuedo dodge to avoid a hit, while the arc from the strike is able to still cut your target. I use this all the time in action combat games; inspired from the “do” strike in kendo); click targeting enemies is even worse.
Turn off auto-targeting and half the skills don’t even work because they need a target (Example: Rangers Hunters Call with the warhorn).
Holding down the click button is also a pain; if you have a programmable mouse or keyboard or a scripting program you can macro the right click to be a toggle-able though.