Depends on what you’re trying to do.
Casually playing PvE you can run anything and spend or save as you want. Baseline gear should be exotic, stats up to your build. Multiple gear sets give better playstyle variety.
Spend some time in the bank’s wardrobe to find a look you want, save up to get it ^.^
Gear, generally berserker is optimized for damage. Sinister for some extra condi punch if your class/build can make use of it. Again for most of the game this doesn’t really matter, it’s more if you want to min/max or do speed runs of stuff. While learning the game it’s ok to get something with more defence and gradually get used to active damage mitigation. Ascended trinkets are easy to get, just takes a bit of time. Ascended weapons are worth the process but cost a fair amount while armor has a high cost and mostly best for fractals or highly competitive WvW.
Laurels are best to hang on to until needed for something. They are the hardest to obtain game currency. Examples of use: special skins at the laurel vendor, t6 bags (for money or legendary crafting), ascended crafting.
It comes down to making goals for that character (need to say what it is for specific advice) then work towards them while having fun. Grinding only as you enjoy it. There’s the option of making additional alts to try their play styles as well.