Blasted Moors
You’re talking about the ruins where the Grendich Gamble JP is located, right? I don’t believe there’s any events in that area which are affecting the spawns, but there are several big “danger zones” in that area. The first is in the small field beside the tower itself, where you’re in the line of fire from several Ghost Cannons, a trebuchet or two, and several rapidly respawning ghost Mages/Archers. Try to avoid that area at all costs, and instead hug the southern crumbled wall. The wall protects you from the trebuchets and lets you avoid the line of fire from the cannons. You can reach the bottom of the tower this way by just killing a few ghosts.
The other major danger zone is the Grendich Courthouse, because there’s also 3 or 4 Veterans in the area. If you’re quick and have a decent health pool, you can run in to grab the POI and run back out again, but otherwise, I would recommend only going in there with another person or two to back you up.