Guild Wars 2

First, add an option in the control menu to center the mouse either when entering or exiting mouse look. This could help a lot with the problem many players have described of losing track of their mouse in combat. It should be optional, so players can decide for themselves if they like it, or possibly even if they prefer to center upon activating mouselook or instead when releasing it.

Second: Allow ground target spells to target through all UI windows. Since skills can be fired via hotkey without clicking the window, you should be able to target the ground behind these UI elements.

The way it currently works activating a GTAE when the mouse is over a UI window causes it to activate directly on top of the player. This can be worse than not firing at all, especially with teleport skills, clipping the edge of the target window can basically cause the spell to fail and go on cooldown.

Allowing targetting through windows would increase the usable space on the screen and would especially benefit players playing at lower resolutions where the UI takes up more of the screen.

I think these two changes would improve the polish and ease of transitioning between GTAoE and mouse look which is a huge part of combat in this game.