Im currently farming for sunrise, and I need lodestones for that, best places are pretty much fractals, the forge, and coe chests. I pretty much run this dungeon every day, and notice a lot of people struggle with it, or flat out refuse to do it because it is too hard, so maybe this will help a little, this is my tactic to conquer the inquest. I play full glass dps mesmer btw
The start
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You fight ice elemtals and wolves, the ice elementals will do a short range aoe ice blast that will 1shot most classes, if you melee it, dodge when it starts, its damage lags by about 2 seconds from the animation, its prefered to range.
Something to keep in mind for all paths, Subject alpha will always do a pboae burning, in addition to his path specific mechanic. On his second and third fights he will spawn undead tendrils. These are EXCELLENT rally tools for when someone goes down. He also imprisons 1 player from time to time. Teleports will remove you from the prison, power based damage is required to break them. At first oppurtunity break free someone stuck in a crystal. On the last fight essences will spawn, and he eats them to heal a small amount, they have a bit too much HP to kill before they get to him because of how fast they move, so just deal with it and dps him harder. If someone goes down during an alpha fight, its less than 50% chance that you can res them because of how fast the aoe comes. Any blocks or invulnerabilities make this fight that much more easy
Turret Golem:
The golem is common to all fights, he is a spank and spank boss, no special tactic is required. The turrets will give him boons, it is recommended that you kill protection and retaliation (if you have enough dmg, else just protection) when they respawn. Ranged dps can dps without fear of taking dmg (except from retaliation) by standing behind the thing just to the left of the doorway. Reflects own this boss.
Path 1
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Subject Alpha:
P1 Alpha fights by dropping a dragon tooth aoe, and then a room aoe in a directional cone.
The dragon tooth is easily avoidable, walk out of it.
The cone is more difficult, I feel its animation is too fast, however it is 100% avoidable, here is the trick, after he casts dragon tooth, he will face his cone target (dragon tooth takes 2 seconds to finish). After dragon tooth finishes, if he is facing you, count to 2, on 2 dodge either sideways, or towards him. It is easiest to accomplish this when everyone spreads out a little or stands on a different side of him.
Hacking the security console:
An endless supply of bombs will appear and explode in your face, they take two or three hits to kill, just kill them while the hacker works.
Have the person with the least power based damage be the hacker.
Everytime a security layer is hacked, 3 golems will appear, kill them before you hack another layer, or you will have to deal with 3 more, and it can quickly get out of hand, this approach is safer than the other approaches ive seen, commonly groups want 4 people to run around like chickens and try to hold agro on the golems and bombs while one person hacks, and it fails quite often resulting in massive gear damage.
Bjarl:
Spank fight, let him charge into a pillar to remove his armor, then dps