Suggestion #1: Add a mouseover menu to the weapon swap button. This menu contains slots (expandable? gem store/black lion item?) that allow players to store alternative weapons. These slots would only be accessible outside of combat.
This would get rid of the process of opening up the inventory and selecting an alternate weapon, making it as simple as hitting a key before entering combat. However, combat options would be unaffected.
Suggestion #2: Allow runes/sigils to salvage into their vendor value in currency. This should have little impact on the economy (beyond the additional cost to salvage rather than vendor, convenience fee?), but help players deal with the obnoxious number of runes/sigils we find.