Guild Wars 2

Some traits have a certain health threshold to activate a certain utility like example
Defy Pain — Activate Endure Pain when you are struck while below the health threshold
Or
Last Refuge — Use Blinding Powder when your health reaches a certain threshold

Do this kind of traits require the utility to be in the slot to be activated?

Not sure if I’m posting it right since this is my first post

For all of my experiences, no, they activate independent of the ones you can activate yourself (that is, Defy Pain can trigger regardless of if you have Endure Pain equipped, and if you activate Endure Pain and put it on cool down Defy Pain can still trigger (and visa versa)). There may be some that interact poorly with overlaps, though.

In case you haven’t, note that they have internal cool downs, so it doesn’t happen every time you go below that threshold.

Nope. They activate their own version of the ski seperate from your skill bar.

Thank you both for replying
That answers all my doubts about the topic