Devona's Armor and Runes
hey Syn!
1) you can change the rune / sigil / upgrades of any gear. you just double click the one you want to apply and it will “overwrite” the current existing slotted upgrade. this means that the original rune (Strength in the case of your example) would be desstroyed or gone. based on my experience, you can keep overwriting runes in armour pieces.
the only limiting factor should be the required level. e.g. if your armor is lvl 10, you can’t put a lvl 60 rune in it.
2) i’ve only read / heard that you can replace sigils in Legendary weapons as mentioned in (1). again, the existing sigil will be permanently gone. i guess you can always replace it again if you want to go back to that. however, i have not tried this myself, though people stated that the legendary status does not change. fwiw, i personally plan to keep my legendary as is and not make any changes to it though.
hope this helps!
Akaigi | Warrior Made of Wood
[CDS] – Sanctum of Rall