Turn off Event Tracking
Here you go: https://wiki.guildwars2.com/wiki/Graphical_user_interface#Content_guide
Good luck.
You can’t hide them completely but if you open the Options menu and change the drop-down for the Content Guide to Hide Events and Personal Story it will just show you map completion stuff. Events will still appear in the text below the Content Guide, but only when you’re in range of them.
(Alternatively you can just look at the map to see what you need to do, but some things, like some POIs can be hard to spot.)
Danielle Aurorel, Dear Dragon We Got Your Cookies [Nom], Desolation (EU).
“Life’s a journey, not a destination.”
“Life’s a journey, not a destination.”