Q:
What's a good rune for thief to use in pve?
It depends, if you are are level 80 or not.
A level 80 thief has more then enough defensive skills and traits to run zerkergear, so Rune of the scholar, mesmer, thief or simular would be great. When leveling I would advise to go a lil bit more defensive. It also depends a lot of your other gear.
Personally, if you are not level 80 yet, I wouldnt worry too much and pick something that you think is usefull.
Arise, ye farmers of all nations
Arise, opressed of Tyria!
Arise, opressed of Tyria!
Mercury has it right. I would like to add that if you are still leveling gems work great, and if you on a budget at 80 ruby orbs are a good budget choice.