Guild Wars 2

Should I use 6 runes of melandru or 4 runes of resistance + 2 runes of the sunless?

If i use 6 runes of melandru, I will gain 90 toughness, but will lose 5% condi reduction. Is this worth it? The 5% extra condi reduction is enough to reach -100% condi duration reduction for cripple, chill and immob. So will I be completely immune to those conditions? Or is there a minimum duration I will be affected no matter what condi duration redution i have equipped?

Stun duration reduction isn’t of concern.

I assume you’re running lemongrass poultry soup food as well as geomancer’s freedom in earth. In my opinion I think the 90 toughness would be worth the condi reduction loss really, as it helps general survivability in the long term than just a negligible shorter condi duration. Whatever you have left over in condi reduction is clearly above 90% so any effects that will immobilize, cripple, or chill will literally be next to nothing already.