Engineer build ( vs mesmers ..)
Condition HGH works fine against Mesmers. If your stunbreaker is up, you should have enough pressure to kill them before you die in the 2nd or 3rd shatter combo.
For d/d eles this also work, but you have a hard time to kill them. Because they have to die in 10sec.
Thiefs with sword/dagger are more or less immune to conditions and steal boons. HgH is real bad against them.