mesmer downed skill 2 and 3 not working
You need a target for each of those skills. Are you sure you had one?
Sometimes 2 will bug from lag and you will use it right away… Otherwise it’s not bugged. And 3 is fine.
This applies to all downed skills on all classes:
If you are doing an action, especially if you have another ‘queued up’, at the same time you are downed, the downed skill will ‘activate’ and go on cooldown. This is notoriously seen if playing a thief due to all the skills being spammable (good way to give some punishment for heartseeker spamming), but seen on other classes too.
As for op’s post, you need to target an enemy for them to activate. However, you should also be getting a message on screen that says, "You must have an enemy targeted”, although can be missed when doing a lot or frustrated.