Multiple severe issues
Just had the sine wave problem myself in the middle of a battle with Jormag
twice, exited and started again, 3 minutes in happened again, never happened
until this latest patch (18th sept).
Strangely enough only in the left channel.
i just now had the very loud pulsing noise in the wvw as well. could not figure out where it was coming from until i closed out of Guild Wars and it stopped. Fairly annoying as i was in the middle of a fight and it was so loud that i could not bare it. Not sure what is causing it.
I had all ambient noise drop while fighting some mobs a little while ago.