Seems I am getting this problem and have had it on and off for a few weeks. Restarting the game has not fixed it tonight, might try rebooting to see if maybe some other process is interfering. YES I checked the menu option to see if it was the problem.
It doesn’t close windows, or pull up the game menu, or stop attacks which is dangerous on a ranger!! ;-) Using Windows 7 Ult. and Logitech G19 keyboard. I have NO remapped keys for GW2 and no macro keys set for the keyboard. Any Ideas from game techs?? I will be glad to reply to any official request for any other testing of this issue!