Yeh I have the same problem since the HoT patch(es). Its an absolutely buggy crashy mess at the moment. The only way I can get the launcher to work again is to go to Library > Application Support and delete the Guild Wars 2 folder. But that only seems to work sometimes, you may have to delete the folder and then restart the computer to flush it properly.
None of this really helps for long considering I crash everytime I’m in Lions Arch without fail.