ive only been playing a few weeks but I would think it depends on what you are doing…
i use matale7’s rune setup of 2x air 2x water 2x speed (could sub in 2x pack if you want) this gives me 52 seconds of swiftness from a 48 second CD signet of rage (i have 10-20 points for boon duartion as well w/ 0% boon duration from trait you still get ~44 seconds of swiftness).
I tend to avoid zergs in wvw and like small squad play, this rune setup lets me have high mobility, solo I use a GS for damage/control/more mobility (which sounds funny but I use 1b to make ppl move) and hammer for more control and eventually a kill combined w/ GS.
w/ small group play I will use WH to help w/ squad mobility and have mainly shouts for utility.
anyways I like having a high mobility and thus 2-2-2 set of runes.