I’m having the same issue as well. Running Eyefinity on 3 monitors. Previously the UI elements were moved to the side monitors and my status/attacks bars were all on the middle monitor.
Since the most recent patch, everything is now pushed to the middle, which is fine, but it’s now partially on the far left monitor and off center. The ma kitten hifted as well. When I attempt to use a fast travel point I have to click to the left and down of where the actual point is shown on the map for it to register.