Guild Wars 2

I like to try and play GW2 with a gamepad and therefore I downloaded XPadder and configured my system and it worked well.
But then I thought that a different configuration would be better, so I when I next time started the game again I begun to configure a new setting with XPadder.
But now nothing works anymore, no button reacts on anything.
What can be wrong?

i think you should ask in technical support forum.

Here is a forum that will help you out:

https://forum-en.gw2archive.eu/forum/game/players/XBox360-controller-mapping-for-Guild-Wars-2-Enjoy/first