Thief PvE armor builds
Could you specify if you are running a condition or a backstab spec?
If you can post it, even better!
backstab spec with full berserker armor
If you want to play glass cannon and have a little more survivability, you can go for runes of divinity and still retain a big part of the damage. Runes of the Wurm/Warrior should also be viable alternatives, depending on your style.
You can certainly mix in some vitality, but after a certain point it stops being a glass cannon spec and your damage won’t be as impressive. Note that you will still be fragile as hell if you don’t dodge/stealth effectively.
Another viable option would be to use something like Blinding Powder for the blind/stealth. In the end, however, the only consistent source of survivability will be your own ability to stay out of harm’s way after dealing your damage.