Honestly it doesn’t really matter what you run. I run full knight’s (weapons, armor, and jewelry), with dolyak runes. Is it optimal? Hell no. Does it work? yes. I do dungeons, open world and WvW with the same gear. I guess what I’m trying to say is, it’s hard to go wrong.
Now if you’re looking for suggestions here are a few. Building tanky is meh, other classes can do it better. If you want some tank i think Knight armor with zerker jewels is a good medium between tank and damage. For runes, Soldiers is a good choice if you use shouts. You could also slot zerker jewels in your armor if you want more damage. For the love of god though, don’t use dolyaks they suck, about 30 hp for the #6….
Anyway don’t take some players too seriously, especially some warriors who think zerker is the only way to go. It works very well for COF1 speed farming but can be a pain for other party member to play with in other places.
Figure out what you use most in your skills, look at this:
http://wiki.guildwars2.com/wiki/Rune
and choose one that makes up a deficiency, or enhances something you are good at. But yeah again, don’t use dolyaks, they suck.