I remap 6-9 & 0 to the thumbpad as well; however I also bind roll, strafe left, strafe right & reverse (thumbpad 10-12). With the option to roll/evade on double press, 10-12 are amazing for your mobility.
Additionally, I remap 5 to ‘E’.
@noblue:
The nice thing about using naga w/ GW2 is that you can use each hand independently for a task. You can split controls so that you can use either your keyboard or the mouse for your mobility while, at the same time, using skills with the other hand. This prevents you having to try to do multiple things with 1 hand at the same time. Does that make a mouse like this necessary? Absolutely not. Does using a mouse like this make you more effective? Possibly, for some people.